人腦微血管內(nèi)皮細(xì)胞是血腦屏障的主要組成成分，并使其能夠限制可溶性和細(xì)胞樣物質(zhì)從血液進(jìn)入大腦。大腦微血管內(nèi)皮細(xì)胞與外周內(nèi)皮細(xì)胞相比具有一些特性：如1）腦微血管內(nèi)皮細(xì)胞有許多細(xì)胞間緊密連接，這些連接造成很高的跨內(nèi)皮阻抗，并能延遲細(xì)胞旁的通量；2）腦微血管內(nèi)皮細(xì)胞缺乏內(nèi)皮細(xì)胞窗孔結(jié)構(gòu)并且其液相物質(zhì)胞飲水平低；3）腦微血管內(nèi)皮細(xì)胞具有不對(duì)稱定位的酶和載體介導(dǎo)的轉(zhuǎn)運(yùn)系統(tǒng)，從而造成“兩極分化”的表現(xiàn)型。?與外周內(nèi)皮細(xì)胞相同，大腦微血管內(nèi)皮細(xì)胞表面表達(dá)細(xì)胞粘附分子以調(diào)控白細(xì)胞進(jìn)入大腦。由于微血管內(nèi)皮細(xì)胞的器官特異性，大腦微血管內(nèi)皮細(xì)胞廣泛用于研究血腦屏障的分子和細(xì)胞機(jī)制。
ScienCell實(shí)驗(yàn)室的HBMEC分離自人大腦組織，原代凍存，冰凍運(yùn)輸。每管細(xì)胞密度超過5×105/ml。細(xì)胞特性經(jīng)vWF/Factor VIII和CD31 (P-CAM)?免疫熒光鑒定，能夠攝取DiI標(biāo)記乙?；兔芏戎鞍?DiI-Ac-LDL)。本細(xì)胞經(jīng)檢測(cè)不含HIV-1、HBV、HCV、支原體、細(xì)菌、酵母菌和真菌。如采用ScienCell?實(shí)驗(yàn)室特制的培養(yǎng)基，可保證此細(xì)胞的良好培養(yǎng)。

推薦培養(yǎng)基：內(nèi)皮細(xì)胞培養(yǎng)基 (ECM, Cat. #1001)

貨號(hào)	1000
產(chǎn)地	美國(guó)
縮寫	HBMEC
規(guī)格	5 x 10^5 /1ml
用途	科研
儲(chǔ)存	液氮
運(yùn)輸	干冰
關(guān)鍵字	人腦微血管內(nèi)皮細(xì)胞 HBMEC 人腦微血管內(nèi)皮細(xì)胞 HBMEC 人腦微血管內(nèi)皮細(xì)胞 HBMEC 人腦微血管內(nèi)皮細(xì)胞 HBMEC 人腦微血管內(nèi)皮細(xì)胞 HBMEC 人腦微血管內(nèi)皮細(xì)胞 HBMEC 人腦微血管內(nèi)皮細(xì)胞 HBMEC 人腦微血管內(nèi)皮細(xì)胞 HBMEC
公司簡(jiǎn)介	合肥星肽生物科技有限公司作為專業(yè)的ScienCell中國(guó)代理商，專業(yè)經(jīng)營(yíng)實(shí)驗(yàn)室科研用原代細(xì)胞、原代細(xì)胞專用培養(yǎng)基、原代細(xì)胞無血清培養(yǎng)基、干細(xì)胞、干細(xì)胞培養(yǎng)基、干細(xì)胞無血清培養(yǎng)基的研究和開發(fā)。合肥星肽生物科技有限公司始終致力于為客戶提供可靠的研究材料以及方便快捷的服務(wù)，對(duì)購(gòu)買項(xiàng)目的前期資料提供,中期合同保證,后期貨物跟蹤到終售后的確保項(xiàng)目準(zhǔn)確到位，都有相關(guān)專業(yè)人士進(jìn)行維護(hù),確保您在合肥合肥星肽生物科技有限公司公司獲得上等服務(wù)！
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